I've shot the 100gr out of a 25-06 and the 110gr out of a .270 Wby. Killed a deer with each rifle last season and they did what I expected them to do. Very accurate out of both rifles. That being said, I've killed plenty of deer with conventional bullets and never had a problem. I'll continue to use these bullets in both rifles until I run out of them. After that, I may go back to a Sierra GameKing.